Abstract P-376

EE 376 A / Stat 376 A Handout

P 376 Phenotypical and genotypical classification of autosomal recessive RP

Pupose:In order to develop a treatment for recessive retinitis pigmentosa the ultimate objective is to introduce a normal copy of the abnormal gene into photoreceptors. The post-mitotic status of photoreceptor cells make them unsuitable targets for existing retroviral vectors. One of the strategies that we have been exploiting is adenoviral (AV) mediated gene transfer. Here we report successful...

376-382 Clinical signi

Bronşiyolitis obliterans (BO)’lı çocuklarda segmental akciğer perfüzyon defektlerinin klinik önemi daha önce rapor edilmemiştir. Bu çalışmanın amacı; BO’lu çocuklarda akciğer perfüzyon defektlerinin klinik anlamının değerlendirilmesi ve izlem üzerine etkisinin açıklanmasıdır. Çalışmaya, yaşları 9-60 ay arasındaki (ortalama ± SD: 17.8 ± 13.4 ay) 38 BO’lu çocuk alındı. Tanı, altı haftadan uzun sü...

Tf-cmte130025 376..380

Background: A school’s learning environment is believed to influence academic performance yet few studies have evaluated this association controlling for prior academic ability, an important factor since students who do well in school tend to rate their school’s environment more highly than students who are less academically strong. Aim: To evaluate the effect of student perception of the learn...

Dmd055491 369..376

Cynomolgus monkeys are a commonly used species in preclinical drug discovery, and have high genetic similarity to humans, especially for the drug-metabolizing cytochrome P450s. However, species differences are frequently observed in the metabolism of drugs between cynomolgus monkeys and humans, and delineating these differences requires expressed CYPs. Toward this end, cynomolgus monkey CYP3A4 ...